Low levels of brain oxygen may boost Alzheimer's risk
Researchers at Canada's University of British Columbia studied mice that had a gene tied to .
The researchers kept some mice in cages with low-oxygen air for 16 hours a day for a month.
They kept the other mice in cages with normal oxygen levels.
In humans, conditions such as stroke that hamper blood flow in the brain can limit the brain's oxygen supply.
After the month, the researchers tested both sets of mice on a memory test.
The mice that had lived in low oxygen performed worse.
Those mice also had more amyloid beta plaque -- a hallmark of Alzheimer's disease -- in their brains, compared to the mice with normal brain oxygen levels.
Under the influence of low brain oxygen levels, the BACE1 gene upped production of amyloid beta, the key protein in Alzheimer's brain plaque.
Even a "slight" rise in BACE1 activity "could lead to a dramatic increase in [amyloid beta] production," the researchers write.
Low brain oxygen levels might also affect other genes and may spur brain cell death, worsening memory in Alzheimer's disease, Song's team notes.
The report appears in Proceedings of the National Academy of Sciences' online early edition.
Polyunsaturated fats: set up chronic inflammatory responses in brain tissue and foster blood damage. They are also harmful to blood vessels and ultimately blood circulation.
EX: safflower, sunflower and corn oils.
These oils are usually included in processed foods such as salad dressings, fries, doughnuts and most margarines. Even worse are hydrogenated vegetable oils. These oils are used in process foods such as micro-wave popcorn, boxed cakes, TV dinners, etc.
Sugar: Eating too much sugar can lead to insulin resistance which upsets the glucose level in the blood. This may lead to permanent damage to brain cells.
Simple carbohydrates turn instantly to sugar within the body.
Some scientist feel that eating white potatoes or white bread is just like eating candy.
Carbohydrates influence mood. There is a delicate balance of the right kind of carbohydrates.
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